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Chloroquine Has a Cytotoxic Effect on Acanthamoeba Encystation through Modulation of Autophagy

Encystation of Acanthamoeba castellanii is associated with resistance to chemotherapeutic agents. Blocking the encystation process could potentiate the efficacy of chemotherapeutic agents and biocides. During encystation, autophagy is highly stimulated and required for proper encystation of Acantham...

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Hlavní autoři: Jha, Bijay Kumar, Jung, Hui-Jung, Seo, Incheol, Kim, Hyun Ah, Suh, Seong-Il, Suh, Min-Ho, Baek, Won-Ki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187977/
https://ncbi.nlm.nih.gov/pubmed/25114131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03164-14
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