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Chloroquine Has a Cytotoxic Effect on Acanthamoeba Encystation through Modulation of Autophagy

Encystation of Acanthamoeba castellanii is associated with resistance to chemotherapeutic agents. Blocking the encystation process could potentiate the efficacy of chemotherapeutic agents and biocides. During encystation, autophagy is highly stimulated and required for proper encystation of Acantham...

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Autors principals: Jha, Bijay Kumar, Jung, Hui-Jung, Seo, Incheol, Kim, Hyun Ah, Suh, Seong-Il, Suh, Min-Ho, Baek, Won-Ki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187977/
https://ncbi.nlm.nih.gov/pubmed/25114131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03164-14
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