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Impact of MIC Range for Pseudomonas aeruginosa and Streptococcus pneumoniae on the Ceftolozane In Vivo Pharmacokinetic/Pharmacodynamic Target

Ceftolozane is a novel cephalosporin with activity against drug-resistant pathogens, including Pseudomonas aeruginosa and Streptococcus pneumoniae. The in vivo investigation reported here tested the limits of this drug against 20 P. aeruginosa and S. pneumoniae isolates across a wide MIC range and d...

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Bibliografiske detaljer
Main Authors: Lepak, A. J., Reda, A., Marchillo, K., Van Hecker, J., Craig, W. A., Andes, D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187960/
https://ncbi.nlm.nih.gov/pubmed/25092700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03572-14
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