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Elongation Factor P and Modifying Enzyme PoxA Are Necessary for Virulence of Shigella flexneri

Elongation factor P (EF-P) is a universally conserved bacterial translation factor. In many bacteria, EF-P is posttranslationally modified by PoxA, which covalently attaches a β-lysine to a conserved lysine residue of EF-P. Here we show that both EF-P and PoxA are necessary for virulence of the huma...

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Detalhes bibliográficos
Main Authors: Marman, Hannah E., Mey, Alexandra R., Payne, Shelley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187845/
https://ncbi.nlm.nih.gov/pubmed/24935977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01532-13
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