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Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence

Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in Shigella flexneri. An S. flexneri clsA mutant had no cardiolipin detected within its membrane, grew normally in vitro, and invaded cu...

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Bibliographic Details
Published in:mBio
Main Authors: Rossi, Rachael M., Yum, Lauren, Agaisse, Hervé, Payne, Shelley M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574711/
https://ncbi.nlm.nih.gov/pubmed/28851846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01199-17
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