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Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence

Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in Shigella flexneri. An S. flexneri clsA mutant had no cardiolipin detected within its membrane, grew normally in vitro, and invaded cu...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Rossi, Rachael M., Yum, Lauren, Agaisse, Hervé, Payne, Shelley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574711/
https://ncbi.nlm.nih.gov/pubmed/28851846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01199-17
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