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rBCG30-Induced Immunity and Cross-Protection against Mycobacterium leprae Challenge Are Enhanced by Boosting with the Mycobacterium tuberculosis 30-Kilodalton Antigen 85B

Leprosy remains a major global health problem and typically occurs in regions in which tuberculosis is endemic. Vaccines are needed that protect against both infections and do so better than the suboptimal Mycobacterium bovis BCG vaccine. Here, we evaluated rBCG30, a vaccine previously demonstrated...

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Detalhes bibliográficos
Main Authors: Gillis, Thomas P., Tullius, Michael V., Horwitz, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187824/
https://ncbi.nlm.nih.gov/pubmed/25001602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01499-13
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