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Listeria-Vectored Vaccine Expressing the Mycobacterium tuberculosis 30-Kilodalton Major Secretory Protein via the Constitutively Active prfA* Regulon Boosts Mycobacterium bovis BCG Efficacy against Tuberculosis

A potent vaccine against tuberculosis, one of the world's deadliest diseases, is needed to enhance the immunity of people worldwide, most of whom have been vaccinated with the partially effective Mycobacterium bovis BCG vaccine. Here we investigate novel live attenuated recombinant Listeria mon...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Jia, Qingmei, Dillon, Barbara Jane, Masleša-Galić, Saša, Horwitz, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563566/
https://ncbi.nlm.nih.gov/pubmed/28630063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00245-17
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