Identification of Novel Coxiella burnetii Icm/Dot Effectors and Genetic Analysis of Their Involvement in Modulating a Mitogen-Activated Protein Kinase Pathway

Coxiella burnetii, the causative agent of Q fever, is a human intracellular pathogen that utilizes the Icm/Dot type IVB secretion system to translocate effector proteins into host cells. To identify novel C. burnetii effectors, we applied a machine-learning approach to predict C. burnetii effectors,...

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Detalhes bibliográficos
Main Authors: Lifshitz, Ziv, Burstein, David, Schwartz, Kierstyn, Shuman, Howard A., Pupko, Tal, Segal, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187803/
https://ncbi.nlm.nih.gov/pubmed/24958706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01729-14
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