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Regulation of Natural mRNAs by the Nonsense-Mediated mRNA Decay Pathway

The nonsense-mediated mRNA decay (NMD) pathway is a specialized mRNA degradation pathway that degrades select mRNAs. This pathway is conserved in all eukaryotes examined so far, and it triggers the degradation of mRNAs that prematurely terminate translation. Originally identified as a pathway that d...

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Detalhes bibliográficos
Main Authors: Peccarelli, Megan, Kebaara, Bessie W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187617/
https://ncbi.nlm.nih.gov/pubmed/25038084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00090-14
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