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Regulation of Natural mRNAs by the Nonsense-Mediated mRNA Decay Pathway

The nonsense-mediated mRNA decay (NMD) pathway is a specialized mRNA degradation pathway that degrades select mRNAs. This pathway is conserved in all eukaryotes examined so far, and it triggers the degradation of mRNAs that prematurely terminate translation. Originally identified as a pathway that d...

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Bibliographic Details
Main Authors: Peccarelli, Megan, Kebaara, Bessie W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187617/
https://ncbi.nlm.nih.gov/pubmed/25038084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00090-14
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