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Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia

In order to identify epigenetic mechanisms through which hyperglycemia can affect gene expression durably in β cells, we screened DNA methylation changes induced by high glucose concentrations (25 mmol/L) in the BTC3 murine cell line, using an epigenome‐wide approach. Exposure of BTC3 cells to high...

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Detalhes bibliográficos
Main Authors: Tros, Fabiola, Meirhaeghe, Aline, Hadjadj, Samy, Amouyel, Philippe, Bougnères, Pierre, Fradin, Delphine
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187575/
https://ncbi.nlm.nih.gov/pubmed/25347859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12076
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