Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia

In order to identify epigenetic mechanisms through which hyperglycemia can affect gene expression durably in β cells, we screened DNA methylation changes induced by high glucose concentrations (25 mmol/L) in the BTC3 murine cell line, using an epigenome‐wide approach. Exposure of BTC3 cells to high...

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Detaylı Bibliyografya
Asıl Yazarlar: Tros, Fabiola, Meirhaeghe, Aline, Hadjadj, Samy, Amouyel, Philippe, Bougnères, Pierre, Fradin, Delphine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley Periodicals, Inc. 2014
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187575/
https://ncbi.nlm.nih.gov/pubmed/25347859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12076
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