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Eccentric contractions disrupt FKBP12 content in mouse skeletal muscle

Strength deficits associated with eccentric contraction‐induced muscle injury stem, in part, from impaired voltage‐gated sarcoplasmic reticulum (SR) Ca(2+) release. FKBP12 is a 12‐kD immunophilin known to bind to the SR Ca(2+) release channel (ryanodine receptor, RyR1) and plays an important role in...

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Detalhes bibliográficos
Main Authors: Baumann, Cory W., Rogers, Russell G., Gahlot, Nidhi, Ingalls, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187567/
https://ncbi.nlm.nih.gov/pubmed/25347864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12081
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