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FKBP12 deficiency reduces strength deficits after eccentric contraction-induced muscle injury

Strength deficits associated with eccentric contraction-induced muscle injury stem, in part, from excitation-contraction uncoupling. FKBP12 is a 12-kDa binding protein known to bind to the skeletal muscle sarcoplasmic reticulum Ca(2+) release channel [ryanodine receptor (RyR1)] and plays an importan...

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Detalhes bibliográficos
Main Authors: Corona, Benjamin T., Rouviere, Clement, Hamilton, Susan L., Ingalls, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519949/
https://ncbi.nlm.nih.gov/pubmed/18511525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01145.2007
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