Carbonic Anhydrase Activation Is Associated With Worsened Pathological Remodeling in Human Ischemic Diabetic Cardiomyopathy

BACKGROUND: Diabetes mellitus (DM) has multifactorial detrimental effects on myocardial tissue. Recently, carbonic anhydrases (CAs) have been shown to play a major role in diabetic microangiopathy but their role in the diabetic cardiomyopathy is still unknown. METHODS AND RESULTS: We obtained left v...

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Autors principals: Torella, Daniele, Ellison, Georgina M., Torella, Michele, Vicinanza, Carla, Aquila, Iolanda, Iaconetti, Claudio, Scalise, Mariangela, Marino, Fabiola, Henning, Beverley J., Lewis, Fiona C., Gareri, Clarice, Lascar, Nadia, Cuda, Giovanni, Salvatore, Teresa, Nappi, Gianantonio, Indolfi, Ciro, Torella, Roberto, Cozzolino, Domenico, Sasso, Ferdinando Carlo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187518/
https://ncbi.nlm.nih.gov/pubmed/24670789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000434
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