Carbonic Anhydrase Activation Is Associated With Worsened Pathological Remodeling in Human Ischemic Diabetic Cardiomyopathy

BACKGROUND: Diabetes mellitus (DM) has multifactorial detrimental effects on myocardial tissue. Recently, carbonic anhydrases (CAs) have been shown to play a major role in diabetic microangiopathy but their role in the diabetic cardiomyopathy is still unknown. METHODS AND RESULTS: We obtained left v...

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Detalhes bibliográficos
Main Authors: Torella, Daniele, Ellison, Georgina M., Torella, Michele, Vicinanza, Carla, Aquila, Iolanda, Iaconetti, Claudio, Scalise, Mariangela, Marino, Fabiola, Henning, Beverley J., Lewis, Fiona C., Gareri, Clarice, Lascar, Nadia, Cuda, Giovanni, Salvatore, Teresa, Nappi, Gianantonio, Indolfi, Ciro, Torella, Roberto, Cozzolino, Domenico, Sasso, Ferdinando Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187518/
https://ncbi.nlm.nih.gov/pubmed/24670789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000434
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