Nalaganje...

Association of phosphatase and tensin homolog low and phosphatidylinositol 3-kinase catalytic subunit alpha gene mutations on outcome in human epidermal growth factor receptor 2-positive metastatic breast cancer patients treated with first-line lapatinib plus paclitaxel or paclitaxel alone

INTRODUCTION: Phosphatidylinositol 3-kinase (PI3K) pathway deregulation (that is PIK3CA mutations and/or phosphatase and tensin homolog (PTEN) loss) has been shown to enhance breast cancer cell survival and confer resistance to chemotherapeutic agents. We studied the prognostic and predictive value...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Xu, Binghe, Guan, Zhongzhen, Shen, Zhenzhou, Tong, Zhongshen, Jiang, Zefei, Yang, Junlan, DeSilvio, Michelle, Russo, Mark, Leigh, Meggan, Ellis, Catherine
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187249/
https://ncbi.nlm.nih.gov/pubmed/25056500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0405-y
Oznake: Označite
Brez oznak, prvi označite!