Metabolic hyperemia requires ATP-sensitive K(+) channels and H(2)O(2) but not adenosine in isolated mouse hearts

We have previously demonstrated that adenosine-mediated H(2)O(2) production and opening of ATP-sensitive K(+) (K(ATP)) channels contributes to coronary reactive hyperemia. The present study aimed to investigate the roles of adenosine, H(2)O(2), and K(ATP) channels in coronary metabolic hyperemia (MH...

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Autori principali: Zhou, Xueping, Teng, Bunyen, Tilley, Stephen, Ledent, Catherine, Mustafa, S. Jamal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
Soggetti:
Integrative Cardiovascular Physiology and Pathophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187071/
https://ncbi.nlm.nih.gov/pubmed/25108010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00421.2014
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