A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α

Remodeling in chronic obstructive pulmonary disease (COPD) has at least two dimensions: small airway wall thickening and destruction of alveolar walls. Recently we showed comparable alterations of the extracellular matrix (ECM) compounds collagen, hyaluoran, and elastin in alveolar and small airway...

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Detalhes bibliográficos
Main Authors: Eurlings, Irene M. J., Dentener, Mieke A., Mercken, Evi M., de Cabo, Rafael, Bracke, Ken R., Vernooy, Juanita H. J., Wouters, Emiel F. M., Reynaert, Niki L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187040/
https://ncbi.nlm.nih.gov/pubmed/25106431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00116.2014
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