Population pharmacokinetics modeling of oxcarbazepine to characterize drug interactions in Chinese children with epilepsy

AIM: To develop a population pharmacokinetics model of oxcarbazepine in Chinese pediatric patients with epilepsy, and to study the interactions between oxcarbazepine and other antiepileptic drugs (AEDs). METHODS: A total of 688 patients with epilepsy aged 2 months to 18 years were divided into model...

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Main Authors: Wang, Yang, Zhang, Hua-nian, Niu, Chang-he, Gao, Ping, Chen, Yu-jun, Peng, Jing, Liu, Mao-chang, Xu, Hua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186992/
https://ncbi.nlm.nih.gov/pubmed/25220641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.76
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