Molecular Dynamics of CYP2D6 Polymorphisms in the Absence and Presence of a Mechanism-Based Inactivator Reveals Changes in Local Flexibility and Dominant Substrate Access Channels

Lignende værker

• Molecular dynamics of CYP2D6 polymorphisms in the absence and presence of a mechanism-based inactivator reveals changes in local flexibility and dominant substrate access channels.
  af: Parker W de Waal, et al.
  Udgivet: (2014-01-01)
• Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
  af: McCarty, Kevin D., et al.
  Udgivet: (2021)
• Membrane Damage and Microbial Inactivation by Chlorine in the Absence and Presence of a Chlorine-Demanding Substrate
  af: Virto, R., et al.
  Udgivet: (2005)
• Intron Presence–Absence Polymorphisms in Daphnia
  af: Omilian, Angela R., et al.
  Udgivet: (2008)
• METOCLOPRAMIDE IS METABOLIZED BY CYP2D6 AND IS A REVERSIBLE INHIBITOR, BUT NOT INACTIVATOR, OF CYP2D6
  af: Livezey, Mara R., et al.
  Udgivet: (2013)