Sex-specific behavioral traits in the Brd2 mouse model of Juvenile Myoclonic Epilepsy

Idiopathic generalized epilepsy represents about 30–35% of all epilepsies in humans. The bromodomain BRD2 gene has been repeatedly associated with the subsyndrome of juvenile myoclonic epilepsy. Our previous work determined that mice haploinsufficient in Brd2 (Brd2+/−) have increased susceptibility...

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Hlavní autoři: Chachua, Tamar, Goletiani, Cezar, Maglakelidze, Giorgi, Sidyelyeva, Galyna, Daniel, Margaret, Morris, Emily, Miller, James, Shang, Enyuan, Wolgemuth, Debra J., Greenberg, David A., Velíšková, Jana, Velíšek, Libor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186774/
https://ncbi.nlm.nih.gov/pubmed/25130458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12160
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