Keratin 5-Cre-Driven Excision of Nonmuscle Myosin IIA in Early Embryo Trophectoderm Leads to Placenta Defects and Embryonic Lethality

In studies initially focused on roles of nonmuscle myosin IIA (NMIIA) in the developing mouse epidermis, we have discovered that a previously described cytokeratin 5 (K5)-Cre gene construct is expressed in early embryo development. Mice carrying floxed alleles of the nonmuscle myosin II heavy chain...

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Bibliographic Details
Main Authors: Crish, James, Conti, Mary Anne, Sakai, Takao, Adelstein, Robert S., Egelhoff, Thomas T.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186751/
https://ncbi.nlm.nih.gov/pubmed/23911870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.07.017
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