Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis

The actin cytoskeleton is a critical regulator of intestinal mucosal barrier permeability, and the integrity of epithelial adherens junctions (AJ) and tight junctions (TJ). Non muscle myosin II (NM II) is a key cytoskeletal motor that controls actin filament architecture and dynamics. While NM II ha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Naydenov, Nayden G., Feygin, Alex, Wang, Dongdong, Kuemmerle, John F., Harris, Gianni, Conti, Mary Anne, Adelstein, Robert S., Ivanov, Andrei I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827066/
https://ncbi.nlm.nih.gov/pubmed/27063635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24161
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