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Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 MAP Kinase

RATIONALE: Aortic stiffening commonly occurs in hypertension and further elevates systolic pressure. Hypertension is also associated with vascular inflammation and increased mechanical stretch. The interplay between inflammation, mechanical stretch and aortic stiffening in hypertension remains undef...

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Autori principali: Wu, Jing, Thabet, Salim R., Kirabo, Annet, Trott, Daniel W., Saleh, Mohamed A., Xiao, Liang, Madhur, Meena S., Chen, Wei, Harrison, David G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186716/
https://ncbi.nlm.nih.gov/pubmed/24347665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.302157
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