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Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 MAP Kinase

RATIONALE: Aortic stiffening commonly occurs in hypertension and further elevates systolic pressure. Hypertension is also associated with vascular inflammation and increased mechanical stretch. The interplay between inflammation, mechanical stretch and aortic stiffening in hypertension remains undef...

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Detalhes bibliográficos
Main Authors: Wu, Jing, Thabet, Salim R., Kirabo, Annet, Trott, Daniel W., Saleh, Mohamed A., Xiao, Liang, Madhur, Meena S., Chen, Wei, Harrison, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186716/
https://ncbi.nlm.nih.gov/pubmed/24347665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.302157
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