miRNA-mRNA integrative analysis in primary myelofibrosis CD34(+) cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by megakaryocyte (MK) hyperplasia, bone marrow fibrosis, and abnormal stem cell trafficking. PMF may be associated with somatic mutations in JAK2, MPL, or CALR. Previous studies have shown that abnormal MKs play a central rol...

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Autors principals: Norfo, Ruggiero, Zini, Roberta, Pennucci, Valentina, Bianchi, Elisa, Salati, Simona, Guglielmelli, Paola, Bogani, Costanza, Fanelli, Tiziana, Mannarelli, Carmela, Rosti, Vittorio, Pietra, Daniela, Salmoiraghi, Silvia, Bisognin, Andrea, Ruberti, Samantha, Rontauroli, Sebastiano, Sacchi, Giorgia, Prudente, Zelia, Barosi, Giovanni, Cazzola, Mario, Rambaldi, Alessandro, Bortoluzzi, Stefania, Ferrari, Sergio, Tagliafico, Enrico, Vannucchi, Alessandro M., Manfredini, Rossella
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186546/
https://ncbi.nlm.nih.gov/pubmed/25097177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-544197
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