miRNA-mRNA integrative analysis in primary myelofibrosis CD34(+) cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by megakaryocyte (MK) hyperplasia, bone marrow fibrosis, and abnormal stem cell trafficking. PMF may be associated with somatic mutations in JAK2, MPL, or CALR. Previous studies have shown that abnormal MKs play a central rol...

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Hlavní autoři: Norfo, Ruggiero, Zini, Roberta, Pennucci, Valentina, Bianchi, Elisa, Salati, Simona, Guglielmelli, Paola, Bogani, Costanza, Fanelli, Tiziana, Mannarelli, Carmela, Rosti, Vittorio, Pietra, Daniela, Salmoiraghi, Silvia, Bisognin, Andrea, Ruberti, Samantha, Rontauroli, Sebastiano, Sacchi, Giorgia, Prudente, Zelia, Barosi, Giovanni, Cazzola, Mario, Rambaldi, Alessandro, Bortoluzzi, Stefania, Ferrari, Sergio, Tagliafico, Enrico, Vannucchi, Alessandro M., Manfredini, Rossella
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186546/
https://ncbi.nlm.nih.gov/pubmed/25097177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-544197
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