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Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

A subset of regulatory B cells (Bregs) in mice negatively regulate T-cell immune responses through the secretion of regulatory cytokines such as IL-10 and direct cell-cell contact and have been linked to experimental models of autoimmunity, inflammation, and cancer. However, the regulatory function...

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Bibliographische Detailangaben
Hauptverfasser: Khoder, Ahmad, Sarvaria, Anushruti, Alsuliman, Abdullah, Chew, Claude, Sekine, Takuya, Cooper, Nichola, Mielke, Stephan, de Lavallade, Hugues, Muftuoglu, Muharrem, Fernandez Curbelo, Irina, Liu, Enli, Muraro, Paolo A., Alousi, Amin, Stringaris, Kate, Parmar, Simrit, Shah, Nina, Shaim, Hila, Yvon, Eric, Molldrem, Jeffrey, Rouce, Rayne, Champlin, Richard, McNiece, Ian, Mauri, Claudia, Shpall, Elizabeth J., Rezvani, Katayoun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186534/
https://ncbi.nlm.nih.gov/pubmed/25051962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571125
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