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The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

The recent cataloging of the genomic aberrations in breast cancer has revealed the diversity and complexity of the disease at the genetic level. To unravel the functional consequences of specific repertoires of mutations and copy number changes on signaling pathways in breast cancer, it is crucial t...

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Main Authors: Weigelt, Britta, Ghajar, Cyrus M, Bissell, Mina J
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186247/
https://ncbi.nlm.nih.gov/pubmed/24412474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.01.001
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