Sulfonylurea versus metformin monotherapy in patients with type 2 diabetes: a Cochrane systematic review and meta-analysis of randomized clinical trials and trial sequential analysis

BACKGROUND: Guidelines recommend metformin as the first-line oral treatment for type 2 diabetes. We conducted a systematic review to assess whether the use of second- and third-generation sulfonylurea agents is associated with benefits and harms in terms of patient-important outcomes compared with m...

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Detalhes bibliográficos
Main Authors: Hemmingsen, Bianca, Schroll, Jeppe B., Wetterslev, Jørn, Gluud, Christian, Vaag, Allan, Sonne, David P., Lundstrøm, Lars H., Almdal, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185978/
https://ncbi.nlm.nih.gov/pubmed/25295236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9778/cmajo.20130073
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