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Trial Sequential Analysis in systematic reviews with meta-analysis

BACKGROUND: Most meta-analyses in systematic reviews, including Cochrane ones, do not have sufficient statistical power to detect or refute even large intervention effects. This is why a meta-analysis ought to be regarded as an interim analysis on its way towards a required information size. The res...

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Dades bibliogràfiques
Publicat a:BMC Med Res Methodol
Autors principals: Wetterslev, Jørn, Jakobsen, Janus Christian, Gluud, Christian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397700/
https://ncbi.nlm.nih.gov/pubmed/28264661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-017-0315-7
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