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Two-tiered biological containment strategy for Lactococcus lactis-based vaccine or immunotherapy vectors

The concept of biological containment was developed as a strategy to prevent environmental dissemination of engineered live vaccine or drug delivery vehicles. A mutation in the gene encoding thymidylate synthase (thyA), a key enzyme in the pyrimidine biosynthetic pathway, has previously been shown t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hanin, Aurelie, Culligan, Eamonn P, Casey, Pat G, Bahey-El-Din, Mohammed, Hill, Colin, Gahan, Cormac GM
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185911/
https://ncbi.nlm.nih.gov/pubmed/24196273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26954
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