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Significant clinical response of progressive recurrent ovarian clear cell carcinoma to glypican-3-derived peptide vaccine therapy: Two case reports

Carcinoembryonic antigen glypican-3 (GPC3) is expressed by >40% of ovarian clear cell carcinoma (CCC) and is a promising immunotherapeutic target. We previously reported the safety of and immunological and clinical responses to a GPC3-derived peptide vaccine in a phase I clinical trial of patient...

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Autori principali: Suzuki, Shiro, Shibata, Kiyosumi, Kikkawa, Fumitaka, Nakatsura, Tetsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185885/
https://ncbi.nlm.nih.gov/pubmed/24252799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.27217
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