O8.08 CIC MUTATION IS A POOR PROGNOSIS FACTOR IN 1P19Q CODELETED GLIOMAS, ASSOCIATED TO AN UP-REGULATION OF PROLIFERATION PATHWAYS

BACKGROUND: Mutations affecting the Capicua transcriptional repressor gene (CIC) on 19q13.2 are frequently associated with a chromosomes 1p and 19q codeletion in oligodendroglial tumors. However, their impact remains poorly understood. EXPERIMENTAL DESIGN: We sequenced the CIC gene on 132 oligodendr...

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Bibliografische gegevens
Hoofdauteurs: Gleize, V., Alentorn, A., Connen de Kérillis, L., Labussière, M., Mangesius, S., Ducray, F., Mokhtari, K., Villa, C., Sanson, M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Oral Presentations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185838/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.69
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