P04.10 PREDICTIVE VALUE OF MGMT PROMOTER METHYLATION QUANTITATIVE ASSESSMENT IN GLIOBLASTOMA, WHICH OPTIMAL CUT-POINT?

BACKGROUND: The methylation in the promoter region of the MGMT gene encoding the DNA repair protein O6-methyl guanine-DNA methyl transferase is a predictive marker for benefit from alkylating agent therapy and a prognostic factor in glioblastoma. Pyrosequencing-based assessement of MGMT promoter sta...

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Bibliografiske detaljer
Main Authors: de Saint-Denis, T., Lerhun, E., Ramirez, C., Devos, P., Maurage, C.A., Dubois, F., Reyns, N., Escande, F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Poster Presentations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185486/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.142
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