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P03.04 SENSITIZING GLIOBLASTOMA CELLS TO THERAPY BY TARGETING THE L-GLUTAMATE/L-CYSTINE ANTIPORTER SYSTEM XC-
Glutamate is the most prominent excitatory neurotransmitter of the brain. Due to its pivotal role, deregulations of the glutamate metabolism have been heavily implicated in various diseases of the CNS. System xc- (SXC), an L-cystine/L-Glutamate antiporter represents the primary non-vesicular route o...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185469/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.127 |
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