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Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates

Neonatal hypoxic ischaemic (HI) injury frequently causes neural impairment in surviving infants. Our knowledge of the underlying molecular mechanisms is still limited. Protein deimination is a post-translational modification caused by Ca(+2)-regulated peptidylarginine deiminases (PADs), a group of f...

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Détails bibliographiques
Auteurs principaux: Lange, Sigrun, Rocha-Ferreira, Eridan, Thei, Laura, Mawjee, Priyanka, Bennett, Kate, Thompson, Paul R, Subramanian, Venkataraman, Nicholas, Anthony P, Peebles, Donald, Hristova, Mariya, Raivich, Gennadij
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185393/
https://ncbi.nlm.nih.gov/pubmed/24762056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12744
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