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Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic‐ischaemic brain damage

Hypoxic‐ischaemic encephalopathy is a leading cause of child death, with high mortality and morbidity, including cerebral palsy, epilepsy and cognitive disabilities. Hypoxia‐ischaemia (HI) strongly up‐regulates Signal Transducer and Activator of Transcription 3 (STAT3) in the immature brain. Our aim...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Hristova, Mariya, Rocha‐Ferreira, Eridan, Fontana, Xavier, Thei, Laura, Buckle, Rheanan, Christou, Melina, Hompoonsup, Supanida, Gostelow, Naomi, Raivich, Gennadij, Peebles, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843952/
https://ncbi.nlm.nih.gov/pubmed/26669927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13490
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