STAT1 Signaling is Essential for Protection against Cryptococcus neoformans Infection in Mice

Non-protective immune responses to highly virulent Cryptococcus neoformans strains, such as H99, are associated with Th2-type cytokine production, alternatively activated macrophages and inability of the host to clear the fungus. In contrast, experimental studies show that protective immune response...

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Bibliographic Details
Main Authors: Wager, Chrissy M. Leopold, Hole, Camaron R., Wozniak, Karen L., Olszewski, Michal A., Wormley, Floyd L.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185263/
https://ncbi.nlm.nih.gov/pubmed/25200956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400318
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