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Resident alveolar macrophages suppress while recruited monocytes promote allergic lung inflammation in murine models of asthma
The role and origin of alveolar macrophages (AMs) in asthma are incompletely defined. We sought to clarify these issues in the context of acute allergic lung inflammation utilizing house dust mite and ovalbumin murine models. Use of liposomal clodronate to deplete resident AMs (rAMs) resulted in inc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185233/ https://ncbi.nlm.nih.gov/pubmed/25225663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400580 |
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