Lipid catabolism via CPT1 as a therapeutic target for prostate cancer

Prostate cancer (PCa) is the most commonly diagnosed malignancy among western men and accounts for the second leading cause of cancer-related deaths. PCa tends to grow slowly and recent studies suggest that it relies on lipid fuel more than on aerobic glycolysis. However, the biochemical mechanisms...

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Detalhes bibliográficos
Main Authors: Schlaepfer, Isabel R., Rider, Leah, Rodrigues, Lindsey Ulkus, Gijón, Miguel A., Pac, Colton T., Romero, Lina, Cimic, Adela, Sirintrapun, S. Joseph, Glodé, L. Michael, Eckel, Robert H., Cramer, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185227/
https://ncbi.nlm.nih.gov/pubmed/25122071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0183
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