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1,25-Dihydroxyvitamin D(3) and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune system has led to an important area of clinical investigation to target these cells for the treatment of autoimmune diseases such as type 1 diabetes. We have demonstrated earlier that in vitro trea...

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Autors principals: Van Belle, Tom L., Vanherwegen, An-Sofie, Feyaerts, Dorien, De Clercq, Pierre, Verstuyf, Annemieke, Korf, Hannelie, Gysemans, Conny, Mathieu, Chantal
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184870/
https://ncbi.nlm.nih.gov/pubmed/25279717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109194
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