1,25-Dihydroxyvitamin D(3) and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune system has led to an important area of clinical investigation to target these cells for the treatment of autoimmune diseases such as type 1 diabetes. We have demonstrated earlier that in vitro trea...

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Main Authors: Van Belle, Tom L., Vanherwegen, An-Sofie, Feyaerts, Dorien, De Clercq, Pierre, Verstuyf, Annemieke, Korf, Hannelie, Gysemans, Conny, Mathieu, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184870/
https://ncbi.nlm.nih.gov/pubmed/25279717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109194
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