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Selective antinociceptive effects of a combination of the N-methyl-D-aspartate receptor peptide antagonist [Ser(1)]histogranin and morphine in rat models of pain

Numerous rather than a few analgesic endogenous neuropeptides are likely to work in concert in vivo in ameliorating pain. Identification of effective neuropeptide combinations would also facilitate the development of gene or cell-based analgesics. In this study, opioid peptides endomorphin-1 (EM-1)...

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Detalhes bibliográficos
Main Authors: Hama, Aldric, Sagen, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184704/
https://ncbi.nlm.nih.gov/pubmed/25505581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.32
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