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Combinations of intrathecal gamma-amino-butyrate receptor agonists and N-methyl-D-aspartate receptor antagonists in rats with neuropathic spinal cord injury pain
Underlying below-level cutaneous hypersensitivity observed following spinal cord injury (SCI) is a concurrent loss of inhibition with an increase in excitation in the spinal dorsal horn. Thus, a dual pharmacological approach, increasing spinal γ-aminobutyrate (GABA) inhibition and decreasing N-methy...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340500/ https://ncbi.nlm.nih.gov/pubmed/22449374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.03.015 |
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