Impact of Numerical Variation in fms-like Tyrosine Kinase Receptor Internal Tandem Duplications on Clinical Outcome in Normal Karyotype Acute Myelogenous Leukemia

BACKGROUND: Impact of single versus multiple fms-like tyrosine kinase receptor 3 internal tandem duplication (FLT3-ITD) mutations on clinical outcomes of patients with acute myelogenous leukemia is not well studied particularly while simultaneously accounting for the quantitative mutation burden. ME...

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Main Authors: Borthakur, Gautam, Kantarjian, Hagop, Patel, Keyur P., Ravandi, Farhad, Qiao, Wei, Faderl, Stefan, Kadia, Tapan, Luthra, Raja, Pierce, Sherry, Cortes, Jorge E
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184417/
https://ncbi.nlm.nih.gov/pubmed/22605576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27571
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