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A disaccharide that inhibits tumor necrosis factor alpha is formed from the extracellular matrix by the enzyme heparanase.

The activation of T cells by antigens or mitogens leads to the secretion of cytokines and enzymes that shape the inflammatory response. Among these molecular mediators of inflammation is a heparanase enzyme that degrades the heparan sulfate scaffold of the extracellular matrix (ECM). Activated T cel...

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Sonraí Bibleagrafaíochta
Main Authors: Lider, O, Cahalon, L, Gilat, D, Hershkoviz, R, Siegel, D, Margalit, R, Shoseyov, O, Cohen, I R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1995
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC41843/
https://ncbi.nlm.nih.gov/pubmed/7761444
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