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Fast spatial ancestry via flexible allele frequency surfaces

Motivation: Unique modeling and computational challenges arise in locating the geographic origin of individuals based on their genetic backgrounds. Single-nucleotide polymorphisms (SNPs) vary widely in informativeness, allele frequencies change non-linearly with geography and reliable localization r...

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Hlavní autoři: Rañola, John Michael, Novembre, John, Lange, Kenneth
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184261/
https://ncbi.nlm.nih.gov/pubmed/25012181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu418
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