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ASAFE: ancestry-specific allele frequency estimation
Summary: In a genome-wide association study (GWAS) of an admixed population, such as Hispanic Americans, ancestry-specific allele frequencies can inform the design of a replication GWAS. We derive an EM algorithm to estimate ancestry-specific allele frequencies for a bi-allelic marker given genotype...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937201/ https://ncbi.nlm.nih.gov/pubmed/27153656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw220 |
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